Kate Plus Eight is a famous producer. He is one of five children; she has three sisters and a brother. Jon is the middle child of three boys. The couple met on October 5, 1997 at a picnic and they were married on June 12, 1999.

They began thinking of having more children and, according to Kate, a biracial infant of a teenage girl named Jamie became available to adopt while Kate was an obstetrics nurse. They decided not to adopt baby Jeremiah, as he was later named, but instead returned to fertility treatment. In October 2003, Kate became pregnant again. Five weeks later, (after being hospitalized for over-stimulated ovaries) at the initial ultrasound, the doctor announced that there were six sacs with seven yolks (embryos). According to Kate, this was emotional news for them. The doctor suggested selective reduction, but the couple was strongly against it.
The sextuplets were born on May 10, 2004, ten weeks premature, which is common in multiple births at Penn State Milton S. Hershey Medical Center in Hershe, Pennsylvania, and were named Alexis Faith, Hannah Joy, Aaden Jonathan, Collin Thomas, Leah Hope and Joel Kevin. All six children were delivered via C-section within a span of three minutes with 75 doctors, nurses and other specialists involved. Because the sextuplets were born in Hershey, they were called "Hershey's Kisses" by the nurses and doctors who delivered them. In late 2008, the family moved from their Elizabethtown, Pennsylvania home to a larger residence in Lower Heidelberg Township, Pennsylvania.